Police responded to the scene in the 4000 block of Underwood Street around 2:35 p.m. after a report of a shooting and a crash.
When they arrived, they found a car that had struck a tree and the victim, Luis Miguel Utrera, suffering from gunshot wounds.
Police say they tried doing CPR on the 19-year-old victim, but he was pronounced dead at the scene.
The University Park Police Chief says this is the first homicide here in a decade. Neighbors say they were in disbelief when they heard about the shooting.
Police have indicated they don't have a suspect or a motive at this time.
Some neighbors believe they heard shots while others didn't, so it is still unclear if the shooter was a passenger or if the shooting happened elsewhere.
If you have any information that might help police in their investigation, call (301) 516-2512.