They say Sylvia Martins was last seen in the 4900 block of Astor Place Southeast on Tuesday, Nov. 26.
She was reported missing on Wednesday, Nov. 27.
Martins has been described as a black female, with a medium complexion. She is about 5-foot-4, and weighs about 170 pounds.
She has brown eyes and salt-and-pepper hair.
If you can help police find her, call (202) 727-9099.