Trump's victory was a psychological boost for his campaign, though the impact on his path to the GOP nomination was still to be determined by the number of delegates he secured. If he captured more than 50 percent of the vote, he would be in strong position to win most of New York's 95 delegates, an impressive haul. [CLICK HERE FOR LIVE RESULTS]
"We don't have much of a race anymore," he said during a victory rally in the lobby of the Manhattan tower bearing his name. His peppered his confident remarks with more references to the economy and other policy proposals than normal, reflecting the influence of a new team of advisers seeking to professionalize his campaign.
"We've got a shot to victory," Sanders said in an interview with The Associated Press. "We have come a very long way in the last 11 months, and we are going to fight this out until the end of the process."
"We must unite the Republican Party because doing so is the first step in uniting all Americans," Cruz said in remarks read off a teleprompter.
Trump needed a strong showing to keep alive his chances of clinching the GOP nomination before the party's July convention -- and to quiet critics who say the long primary season has exposed big deficiencies in his campaign effort.
Cruz is trying to stay close enough in the delegate count to push the GOP race to a contested convention. Cruz's campaign feels confident that it's mastered the complicated process of lining up individual delegates who could shift their support to the Texas senator after a first round of convention balloting.
Trump's political strength, though he boasts of drawing new members to the party, has left some Republicans concerned that his nomination could splinter the GOP. Among Republican voters in New York, nearly 6 in 10 said the nominating contest is dividing the party, according to exit polls.
Among Democrats, Clinton has 1,758 delegates to Sanders' 1,076. Those totals include both pledged delegates from primaries and caucuses and superdelegates, the party insiders who can back the candidate of their choice regardless of how their state votes. It takes 2,383 to win the Democratic nomination.